Short-Term Chilled Storage of Zebrafish (Danio rerio) Embryos in Cryoprotectant As an Alternative to Cryopreservation

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Title: 1 SHORT TERM CHILLED STORAGE OF ZEBRAFISH (Danio rerio) EMBRYOS IN 2 CRYOPROTECTANT AS AN ALTERNATIVE TO CRYOPRESERVATION

23 As zebrafish embryos never been cryopreserved, we developed a protocol to store zebrafish embryos 24 (50% epiboly5.3 hpf) for up to 18 h at 0° C. Initial experiments to optimise cryoprotectant solution 25 demonstrated improved embryo hatching rate following chilling at 0°C for 18 h with 1 M MeOH + 26 0.1 M sucrose (56 ± 5%) compared to other combination of methanol (0.2-, 0.5 M) and sucrose ...

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Present study reports the response of zebrafish embryos exposed in vivo to graded concentrations of Nonylphenol (NP), ranging from high lethal levels to lower, more environmentally relevant levels. Embryos treated with NP showing developmental abnormalities and morphological alterations in a dose-dependent pattern. Results suggest that early exposure to NP can cause direct and delayed mortaliti...

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Danio Rerio, the Zebrafish

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BIOLOGY OF ZEBRAFISH, Danio rerio

Zebrafish, Danio rerio (Hamilton), is one of the most important vertebrate model organism in genetics, developmental biology, neurophysiology and biomedicine (Rubinstein, 2003; Amsterdam and Hopkins, 2006). It is a small, robust fish, so large numbers can be kept easily and cheaply in the laboratory, where it breeds all year round. Development is rapid, with precursors to all major organs devel...

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ژورنال

عنوان ژورنال: Zebrafish

سال: 2015

ISSN: 1545-8547,1557-8542

DOI: 10.1089/zeb.2013.0961